An efficient and environmentally benign chemical synthesis of testolactone

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An Efficient and Environmentally Benign Chemical Synthesis of Testolactone

Testolactone was obtained commercially by microbial transformation of either testosterone or progesterone and also synthetically, albeit in low yield. The only chemical synthesis of 1 so far described in the literature starting from dehydroepiandrosterone (2) is shown in Scheme 1. The strategy followed in this synthetic approach consisted in the initial formation of the lactone ring by a Baeyer...

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ژورنال

عنوان ژورنال: Journal of the Brazilian Chemical Society

سال: 2003

ISSN: 0103-5053

DOI: 10.1590/s0103-50532003000600013